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The signature wave shapes from extracellular recording of neuronal activity display a great variety of shapes with triphasic signals predominating, and pharmacologically targeted ion channels with tetrodotoxin, tetraethylammonium,aminopyridine, and monensin to verify these hypotheses. The signature wave shapes from extracellular recording of neuronal activity display a great variety of shapes with triphasic signals predominating, and pharmacologically targeted ion channels with tetrodotoxin, tetraethylammonium,aminopyridine, and monensin to verify these hypotheses. Christof Koch. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the In this paper, we outline an approach to these problems. Table of ContentsThe Membrane EquationLinear Cable TheoryPassive Dendritic TreesSynaptic InputSynaptic Interactions in a Passive Dendritic TreeThe Hodgkin-Huxley Model of Action-Potential Generation Koch presents what can be now considered to be ‘classical’ computational neuroscience, for example, kinetic models of axon excitability and the work of Hodgkin and Huxley, or linear cable theory and the work of RallBiophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons TLDR. Ray Perrins. PDF This single-authored textbook focuses on the repertoire of computational operations available to individual nerve cells. Expand. Expand. More PDF PLUS. We will review a number of different biophysical mechanisms such as synaptic interactions between excitation and inhibition, dendritic spines, non-impulse generating membrane nonlinearities and transmitter-regulated voltage channels TLDR. PDF Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons TLDR. Expand. PDF Biophysics of Computation: Information Processing in Single Neurons. The signature wave shapes from extracellular recording of neuronal activity display a great variety of shapes with triphasic signals predominating, and pharmacologically targeted ion channels with tetrodotoxin, tetraethylammonium,aminopyridine, and monensin to verify these hypotheses.
